The church already existed in the 16th century. According to a manuscript, the church land was purchased according to a 1503 manuscript titled “Three Horans” and a deed bearing the Sultanate’s seal.
In 1805, Krikor Amira Kevorkyan-Cherazyan, trustee of the Galata Surp Lusavoriç Church, discovered the proof of purchase of the church land, along with other manuscripts, with the cooperation of members of the congregation. He virtually repurchased the land and built the Saint Etchmiadzin children’s school. He later converted the school into a church with the decree he obtained, and the church was consecrated with the name “Amenasurp Yerrortutyun” by Archbishop Alixan, the representative of Saint Etchmiadzin, in 1807. Although there were attempts to rebuild the church, which was reduced to ashes in 1810, they were unsuccessful.
The foundations of the current church were laid in 1836. Reconstruction efforts began with the decision of the Congregational Council under the leadership of Patriarch Matteos Chuhaciyan. Baghdasar Amira Kasbaryan-Cherazyan was appointed trustee. The architects of the church were Garabed Amira Balyan, Hovhannes Amira Serveryan, and Usta Minas Agha. Construction was completed in two years and opened for worship by Patriarch Isdepanos Aghavni in 1838.
A section of the church was repaired again in 1845. In 1846, a building was built next to the Naregyan school in the courtyard, which was later used as an orphanage. This building was converted into a dispensary in 1897. The church and its complex cover an area of 1000 m2. The paintings in the church bear the signature of the painter Hacı Mıgırdiç Bıçagyan. The church has an arched ceiling in the Greco-Roman basilica style. The interior reflects the Corinthian style. The building underwent significant repair and restoration in 1989, and its final restoration took place in 2000, when it was consecrated and opened to worship by Archbishop Şahan Sıvacıyan.
Those buried in the church complex:
Catholicos Hagop Çuğayetsi (1598-1680)
Patriarch İknadios Kakmacıyan (1827-1869)